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Jamie Reed's avatar

I am trying to find the two comments regarding bicalutamide, sorry I am not able to respond directly underneath them. My response is yes but...yes bicalutamide is an androgen 'blocker' but it does not function in the same way that the word 'blocker' does in pediatric gender medicine and therefore we attempted to make great effort to ensure that parents and young people did not equate the two.

When working with the general public in medicine it has been part of my training and my professional role to work to ensure medical literacy and comprehension. Those that work with me know that I often will ask for edits and changes because we always seek to reach the general public at a "6th grade comprehension" level.

One of the ways that I can ensure patients and their families understand what I am conveying is to employ a method called a "teach back" that means that I explain a medical concept and then I ask the patient to teach it back to me.

When working with bicalutamide part of my job was to ensure that patients and their families and especially those providing informed consent understood clearly that bicalutamide was NOT functioning like a BLOCKER, because the general populations understanding of a BLOCKER is that it is completely REVERSIBLE. Bicalutamide is not reversible, once breast tissue changes the only way that can be changed is through surgery.

Bicalutamide is also a different kind of BLOCKER in that is does not work to stop the production of those hormones in the brain but rather gets in the way of the receptors being able to accept testosterone (its a lock/key concept) in all of the cells that are seeking testosterone.

Because I knew what our goal was in the clinic in terms of education I knew that we did not do a good job in educating and properly consenting this parent.

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Wee's avatar

Very good explanation. Shows why you’re so successful in convincing on these issues.

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Daniel Junas's avatar

One further observation. The justification from puberty blockers has slid from helping the subjects pass when they become adults, to providing time to think, to providing some kind of short-term relief. It’s a treatment in search of a rationale. And every rationale fails miserably.

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Eliza Mondegreen's avatar

Treatment in search of a rationale is a great way to put it.

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dd's avatar

Goal-post moving is a constant in gender world.

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Andrea's avatar

It’s that queering behaviour, isn’t it? Everything moves, nothing stays static in meanings or anything really. Totally useless ideology to base any rights from as having words mean certain things is essence of lawmaking.

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Julia Mason MD's avatar

I have so much I want to say . . .

OK, first, I think Azeen is a bit of a chameleon. She mirrors whomever she is talking to. I've talked to her for hours over the years and until 2023 she was willing to pick my brain forever, but never quote me, because I didn't fit into her storyline of Dems for, Republicans against.

In August of 2023 she was writing about the AAP re-upping their terrible horrible no good very bad Statement of 2018 but also, for some reason, saying they were going to do a systematic review of the evidence. They wouldn't say why, but Azeen knew why, and she talked to me before my clinic and again during my lunch hour, trying 17 different ways to get me to say I was in favor of state bans. I was not. In the end, I like my quote in her article, it was "we are making strong recommendations based on weak evidence." But it wasn't what she wanted.

There's a reason we call her the dread Azeen - you talk to her for hours, it really seems like she's picking up what you're putting down, and then you read what she publishes and it's a big disappointment. (I have some empathy for her, she is in a super hostile environment, but really it's mostly disappointment.) She interviewed me for this podcast, fancy microphone and everything, but I didn't make the cut AFAIK. I don't fit in her framing of the situation.

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Lisa Selin Davis's avatar

Let's have you come on and talk about this!!

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Julia Mason MD's avatar

I would love to!

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dollarsandsense's avatar

Brings to mind what Janet Malcolm said about journalists doing what is morally indefensible, soliciting intimacies in order to crush.

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Kara Dansky's avatar

When I spoke with her a few years ago, she asked me, "Wow, why doesn't the press do a better job of covering all of this?" I was like, "Um, hello, you're a NYT reporter! Why are you asking ME that question?!"

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Kim's avatar

This NYT podcast detailing theDutch protocol showed me there is as much similarity to Dutch Protocol and the American version as there is my old lady chair Yoga to Dallas Cowboy Cheerleaders routines.

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Emily's avatar

Thank you for sharing. This is so enlightening and tracks with what Jamie said about Azeen acting differently when Austen was with her.

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Aneladgam Varelse's avatar

I really liked Cori's question "what are you treating", eye-opening

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Daniel Junas's avatar

Your best episode so far. Not just because of the importance of the topic but also because it was a focused conversation. You each brought your best. I hope you will emulate this approach in future episodes.

It is especially a privilege to share Jamie’s journey, from true believer to apostate. Your struggle with this difficult subject is an authentic one, and the others provide useful perspectives. More, please.

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Suzanne's avatar

Thank you so much for this sober and nuanced conversation. I feel gratitude and also great sadness. What I'm now thinking of as the "fruit basket" model of medicine is deeply misguided and so wrong. Thank you again to Cori for his 2022 WaPo piece (https://www.washingtonpost.com/opinions/2022/04/11/i-was-too-young-to-decide-about-transgender-surgery-at-nineteen/). And, Jamie, thank you for filling in so thoughtfully some of the big gaps in The Protocol. Without trying to define "gender" or "gender identity" and without considering the "what if" you four explore at the end of this podcast "maybe we do the harder work to change society [to accept gender non-conformity]", the NYT has done more harm than good.

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Susan Scheid's avatar

Thank you so much for this fascinating and enlightening conversation. Everyone’s questions of Jamie were so thoughtful and searching. I particularly appreciated Jamie’s recounting of how and why her thinking changed over time—and it makes such a lot of sense. The combined knowledge and experience the four of you have on these issues is truly powerful.

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Joaniepatricia@gmail.com's avatar

I am so grateful for you Jamie for choosing to come out as a whistleblower. Please forgive yourself for any harm you believe you have done by supporting this center. As a psychotherapist....sometimes I need to remind myself that clients will make poor decisions for themselves and I have no control over that. Even their youngness and naivete is not in my hands. We all have our journeys.

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RJ in NY's avatar

Thank you so much for doing this. While I realize “I am not the audience,” I was trying to listen as someone more new to all this, and I commend you all.

Thanks for linking to “The Myth of Reliable Research.” (For anyone who’s curious, I also recommend the conference talk given by one of its authors, Zhenya Abbruzzese in 2023: https://youtu.be/XrqLcAff9iI?si=R2Jh-StQ3_D3_WR1 Don’t be deterred by the sensational, “shouty” title frame. It’s a thoroughly scholarly talk.)

Key parts of your conversation also reminded me of Episode 1 of “Gender: A Wider Lens,” titled “Trans: Identity vs. Dysphoria,” where Stella and Sasha discuss these competing perspectives. (For anyone who’s curious, it’s here: https://podcasts.apple.com/us/podcast/gender-a-wider-lens/id1542655295?i=1000502801877)

Many thanks again, Jamie and your Informed Dissent crew members—and much respect.

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RJ in NY's avatar

P.S. to anyone new to all this: I recommend this 2023 memo as an excellent explainer— https://transpolicy.substack.com/p/trans-memo

Its author (pen name “Orlando”) has personal experience regarding cross-sex ideation.

P.P.S. Let me also put on your radar this group, if you don’t already know of it: Democrats for an Informed Approach to Gender (DIAG). Good group.

http://www.di-ag.org/

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RJ in NY's avatar

Thanks! & sorry about the bad link! (I think I’ve fixed it in my comment now.)

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Sylph11's avatar

I was a tomboy, came out as soft butch dyke at 18yo in 1978- If I were a teenager today, and asked about my dislike of having to behave like a girl, dress like a girl, etc.- I would be transitioned! Thank you for the in-depth discussion.

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dollarsandsense's avatar

Thanks for a great episode--such thoughtful discussion, as usual.

I went "grrrrr" when I learned what the Protocol left out in that recording of that parent yelling at Jamie. When there's an actual fact--about a dangerous drug given a child--it's edited out. When it turns out the parent did not know what the drug was, the horror was complete.

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Ute Heggen's avatar

The NY Times follows the Trans Journalists' Association Style and Coverage Guide, which demands news outlets not to report any negative results (family alienation, detransitions, increased not decreased suicides, serious health outcomes and lack of psychological healing) of "affirmative care." I suggest to Informed Dissent panel to go over "The Protocol" episode by episode, keeping in mind that you will have new viewers who need every detail explained, as they will have found you from looking up Jamie Reed. Eliza (Sarah) and you have information about the long term results of the Dutch Study subjects which have not been published, from your attendance at one of their seminars. While you 5 can almost speak to each other in code and use abbreviations for so many details, the general public has been in the dark on this. Cori is very good about asking questions to clarify for the non-initiated, but even then many details, chronologies and personalities must be explained. Especially when discussing the "FG" and "Manon" cases, where FG is a natal female and Manon is a natal male. Unfortunately, the facts about The Dutch Study (DeVries, Cohen-Kettenis, Steensma et al, 2014) must be driven home, with the ever diminishing subject numbers, the skewed measures of "satisfaction" and researcher bias told in excruciating detail. The general public believes researchers are vetted, that they don't hide bad results, that they consider influence in being funded by pharma companies and they strongly believe in their mission to create opposite sex mannequins. This is partly Dutch arrogance, a historical fact since the building of the sea walls and water-pumping windmills to create arable land 900 years ago. It is all of a piece.

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Inga Bullen's avatar

Ah yes! Man battles against natural forces. Interesting thought that it may be a cultural attitude.

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Sapphic Sue's avatar

I wish I could give you a hug, Jamie, thank you for what you are doing x

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Evelyn Ball's avatar

Jamie Reed’s vision towards the end of this episode is of utmost importance: “We didn’t teach true tolerance…instead we just reinforced…those were the moments…imagine where we’d be now if…”

Jamie explains the Dutch had a choice and they took the path to change FG’s body instead of helping and working on the environment that would meet her needs: “…or we do the actual hard thing and work with FG’s parents…”

Such an important episode. Jamie Reed’s thoughts on what the Dutch could have and should have done needs to be turned into a true progressive protocol, mental health standards of care, and a curriculum for teachers.

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dollarsandsense's avatar

When the lack of data about people's actual medical condition, not to mention life functioning, came up, I wanted to yell, "There's no objective measurement, anywhere!"

The only thing measured seems to be self-reports of mental states.

That is a poor metric for obvious reasons. People may want to insist they are okay, even if they aren't. Without assessing objective markers, both physical and functional, there's no way to know. Which, I suppose, is what the ideologues want.

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Aneladgam Varelse's avatar

re: what's the difference between proto-gays who grow up to be gay and not transition vs these who transition or transition in adulthood

Imo the difference is trans ideology on table and simple subsumption of how you are to diagnostic criteria. Part of why I thought I'm trans (I'm female desister) was my childhood history, because I was very gender non-conforming kid and criteria applied to me - BUT in childhood I was sure I'm girl and was perpetually confused by misgendering.

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Eliza Mondegreen's avatar

>> Imo the difference is trans ideology on table and simple subsumption of how you are to diagnostic criteria

I think that's the difference. With FG and his friend who grew up to be a butch lesbian, it's like, OK, FG had homophobic father who wasn't comfortable with FG being gender-nonconforming, aunt who read a book about transsexuals and suggested it, mother who picked it up and took FG to gender clinic, FG learned puberty suppression was an option and then had to have it. That's how you make a 'trans' kid.

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